As schools become increasingly diverse, there is an increasing need for examples of classroom practices that create inclusive teaching and learning environments. Many research studies found that gaining knowledge of student home life and using it to bridge learning and home supports access and equity. Many scholars have called for exemplars of activities that connect students’ in-school and out-of-school cultural activities. This paper provides an example that may be used in teacher education and K–12 classrooms to bridge out-of-school and in-school activities. In this paper, we discuss the enactment of biography-driven instruction, specifically how cultural biographies can be used to create inclusive mathematics teaching and learning.