The study analyzed the level of employee productivity and identified factors influencing employee productivity in listed manufacturing firms in southwestern Nigeria. The descriptive survey design was adopted for this study. A sample of 394 respondents was selected using a simple random sampling technique. Data collected using a structured questionnaire were analyzed using descriptive and inferential statistics. The study showed that a majority of the respondents (58.33%) had average productivity levels. Results further revealed that management and organizational factors were identified as having the greatest influence on employees’ productivity, followed by organizational/technical factors, and then production and finance factors. In addition, results indicated that financial (B = -1.322, p = 0.000), management (B = -2.751, p = 0.000), personal (B = -2.721, p = 0.000), and organizational factors (B = -3.140, p = 0.000) all had significant and negative influence on workers’ productivity. The study concluded that financial, management, personal, and organizational factors were potent factors that could define workers’ productivity.