Rapid developments and change have culminated new applications of information technologies. This trend is reflected in the plethora of innovative studies. Literature indicates that small- to medium-sized enterprises (SMEs) perceive human resources information systems (HRIS) as complicated and time consuming, resulting in resistance from both users and employees. The purpose of this article is to identify necessary acceptance conditions for a successful implementation of the HRIS software within SMEs in Turkey. SMEs compose 99% of all companies in Turkey. Fierce rivalry within sectors gives rise to increased technology use to gain a competitive advantage. This study contributes to an efficient implementation of widely used HRIS in SMEs and offers solutions for implementation failures, including user resistance and idle system problems. This study attempts to apply the technology acceptance model to 112 SMEs that implement HRIS exclusively with all the submodules. This research analyzes success factors for an effective HRIS implementation by testing the latest integrated model of expanded technology acceptance. It concludes that there is a positive and robust correlation between acceptance and use of technology variables and user satisfaction. The results of this study are useful not only for the managers but also for the manufacturers, technical support, online support, and aftersales services as they are advised to develop strategies for user satisfaction.