ORCID
0009-0007-1109-3272
Abstract
Coronary heart disease (CHD) is a leading global cause of mortality, notably affecting postmenopausal women. Hormonal fluctuations during menopause contribute to dyslipidemia, fostering cardiovascular disease (CVD). This study explored lipid profiles among postmenopausal Pakistani women, focusing on the atherogenic index of plasma (AIP) and its association with CHD.
The data consisted of surveys from 265 women aged between 40–70 years. A STEP-wise approach, using a questionnaire from the World Health Organization, was employed for data collection. This quantitative cross-sectional study, guided by the socioecological model, examined links between AIP, age, lipid profiles, and hypertension. The AIP’s association with CHD was analyzed by multiple linear regression. Findings revealed age (β =0.406, p = 0.021), hypertension (β = 0.141, p = 0.002), and cholesterol (β = 1.557, p < 0.001) were significantly associated with AIP, while LDL (β = -1.527, p < 0.001) TG (β=0.790, pβ = -0.426, p = 0.001) were linked with AIP cholesterol.
Implications include the need for patient-centered screening initiatives and preventive measures to improve the quality of life for postmenopausal women. Monitoring and addressing dyslipidemia patterns can reduce the burden of interventional cardiology in Pakistan and enhance community health.
