This study utilized the four-level social-ecological model to provide a better understanding of the disparities in health-related outcomes in high- and low-density African American (AA) communities. The current research sought to understand the relationships between mental and physical health, social-economic factors, and physical environment within this community. The goal of this study was to understand the relationship between these indicators of health, to better inform health-care strategies. The results highlight the significant difference between high- and low-density AA communities and socio-economic factors, physical environment, poor physical days, and poor mental health days. Implications for behavioral health providers are explored.