The influence of specific pretreatment variables (i.e., age, gender, birth order, number of children in the family, and family history of enuresis) on outpatient urine alarm treatment outcomes was examined. A total of 186 Israeli children between the ages of 4 to 7 participated in the study, and of those, 55 children were 4 years old. The entire sample was used to test the age-related pretreated variable, and all other pretreatment variables were solely analyzed using the sample of 4-year-old children at the time of treatment. The data were derived from two different sources: (a) treatment files from a clinical psychologist, and (b) a six question telephone survey. Statistical analysis revealed evidence that family history is a positive predictor of urine treatment outcomes in young children. For young children with a family history of bedwetting, 71.9% were dry post- treatment, while only 43.5% of young children without a family history of bedwetting were dry post-treatment. Other statistical analysis showed no evidence (p > .05) of pretreatment variables’ (i.e., age, gender, birth-order, and number of children in the family) influence on urine alarm treatment outcomes in young children. The findings indicate that, in young children, a family history of bedwetting is a positive predicator for urine alarm treatment outcomes. Pediatricians and other pediatric health practitioners are encouraged to treat young children with a family history of bedwetting with a urine alarm treatment approach.