Date of Conferral

8-20-2025

Degree

Doctor of Nursing Practice (DNP)

School

Nursing

Advisor

Cathy Fant

Abstract

The chosen approach for the Doctor of Nursing Practice (DNP) project was a clinical practice guideline (CPG) on interventions to improve antidepressant medication adherence in adults diagnosed with depression in an outpatient setting. The consequences of medication nonadherence in patients with depression are devastating for individuals and the healthcare system. Therefore, addressing it within nursing practice is essential to improve treatment efficacy and patient outcomes. The practice question related to the DNP project was to determine whether the CPG could improve antidepressant medication compliance in adults diagnosed with a depressive disorder in an outpatient setting. I aimed to develop a CPG on evidence-based practice approaches to reduce a gap in practice and improve patient outcomes. The developed guideline was derived from a literature search that included systematic reviews, meta-analyses, RCTs (randomized control trials), cohort studies, qualitative studies, and literature reviews. Four designated experts used the AGREE II tool to evaluate the developed CPG. All four expert reviewers judged that the developed guideline was of high quality and recommended it for the designated organization and other psychiatric outpatient settings, enabling adults with depression to get equitable, just, and fair healthcare services. By reducing the gap in nursing practice, the CPG could positively affect the organization's standards of care, increase patients' quality of life, reduce healthcare costs, and promote positive social change.

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