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The health of members of the clergy is understudied despite their exhibiting high stress and mortality rates. Grounded in self-regulation theory and using logistic regression, this study of 129 clergy determined the relative strength of stress, coping, health perceptions, age, and years in ministry in predicting health outcomes (chronic disease). Results indicated that as negative coping style and age increased, chronic disease also increased. Health professionals can use these results to improve health outcomes in clergy.