The growing economic pressures, rising awareness of the importance of environmental protection, and stringent global regulations are leading to more integration of sustainability initiatives into corporate strategies across multiple industries. These sustainability initiatives can alter organization cultures and affect employee perceptions and organizational outcomes. In this study, 331 respondents from a wide variety of industries in the South were surveyed. Results showed that companies’ overall green/sustainability orientation is related to organizational culture, quality management maturity, and companies’ performance. The findings implied that it is imperative to develop an organizational culture that is supportive of quality and sustainability to ensure the success of the green initiatives.