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Clients who suffer from opioid use disorders are at an increased risk of overdose and death. Researchers have indicated the need for studies that focus on ways to increase the use of evidenced-based practices (EBPs) in opioid use disorder treatments. Previous research suggests that motivational interviewing (MI) is an EBP that is effective in promoting behavioral change. The purpose of this study was to contribute to the research on MI by examining which variables predict mental health provider use of MI when treating opioid-dependent clients. The theory of planned behavior was the chosen theoretical framework for this study because it allowed an investigation of the mechanisms of action related to MI, and then test whether the MI attitudes and knowledge of mental health providers predicted the use of MI. A cross-sectional survey, with 71 participants, was used to collect data using Leffingwell’s motivational interviewing knowledge and attitudes test. Results of the linear regression tests indicated that neither attitudes towards nor knowledge of MI were predictors of likelihood to use MI. The insight gained from this research may contribute to positive social change by aiding researchers in creating more effective MI training protocols, as well as contribute to the current scholarly literature that serves as the foundation for understanding what constitutes effective opioid treatment.