Genome Sequencing Practices and the Future of Clinical Research
Abstract
Genome sequencing is one of the latest technologies to be introduced for use in clinical trials. It is often used in the practice of genomic medicine, with the objective of processing information about genes and markers to treat disease. Specifically, genomic medicine uses DNA and RNA platform sequencing technologies to analyze the human genome to detect diseases caused by gene mutations. In 2003, these genomic sequencing platforms (first- and secondgeneration sequencing technologies) made it possible to complete the Human Genome Sequencing Project, which identified approximatively 35,000 genes in sequences of more than 3 billion human DNA and RNA chemical bases. This paved the way for genomic medical practice, enabling researchers to carry out translational genomic clinical studies that have begun advancing the clinical trial process in multiple ways.
