Impact of Invasive Fungal Infections on Mortality, Length of Hospital Stay, and Costs in Allogeneic Hematopoietic Stem Cell Transplant Patients

Jenny Cai
Angela Prehn

Abstract

Over the last decade, unrelated donors have become a vital resource for hematopoietic stem cell transplantation (HSCT) and the number of allogeneic HSCT (allo-HSCT) has increased significantly. While invasive fungal infections (IFIs) remain major concerns in these patients, data regarding impact of these infections on mortality, length of hospital stay, and hospital charge are limited in the United States at a national level. Additionally, with many updates in transplant practice, risk factors for IFIs in these patients may have changed.